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The collection comprises one manuscript volume of notes on lectures delivered by John Hunter, Surgeon Extraordinary to King George III, at the operating theatre in Great Windmill Street, London, summarised under the general heading 'The true principles of surgery'. The subject of the lectures include comparison of plant and animal life, such as sensation and movement; treatment of inflamed organs; the effects of poisons; bone fractures; and the identification and cure of various diseases including those of the urinary tract and reproductive organs, 1777.